Disse fremstilles ved industriell behandling av ekstrakter fra valmue eller kjemisk produksjon uavhengig av opiumråstoff, for eksempel oksykodon og fentanyl.Ravkjeder er et tradisjonelt europeisk middel mot kolikk eller tannsmerter på grunn av de påståtte smertestillende egenskapene til ravsyre, selv om det ikke er bevis for at dette er et effe
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